Article: Excipient Selection in Topical Process Development

This article is taken from Pharmaceutical Manufacturing and Packing Sourcer October 2023, pages 92-94. © Samedan Ltd

Unlike solid dosage drug products and sterile injectables, topical and transdermal formulations often contain a higher number of excipients, making them more complex to develop and scale. Given that the processes that can be used for manufacturing a drug product are largely impacted by the specific components of that product’s composition, a strong comprehension of the formulation is key.

Throughout drug product development, it is critical to understand the excipients, processing parameters, and quality attributes specific to the product so that optimal excipients and manufacturing methods can be established for future commercialization.

In this article with PMPS, MedPharm’s Head of Process Development, Joseph Holt, discusses the critical role that excipient selection plays in process development, and the importance of working with a reliable development partner.

Read the full article here.