Poster: Development of a bacterial infection wound model in human ex vivo skin explant for preclinical drug discovery
The infiltration of bacteria and subsequent infection of a wound is a common problem worldwide. This problem is exacerbated by hospital-acquired infections and the growing epidemic of antibiotic resistance.
In an effort to develop a model of skin wound infection, S. aureus and Ps. aeruginosa were chosen as representative bacteria based on their prevalence in human skin and soft tissue infection.